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Benzo Switcher

Because one Benzodiazepine is not the same as another

It is not customary to substitute one Benzodiazepine (BDZ) treatment for another. However, sometimes it happens that we are obliged to do this, particularly when switching from the oral to the subcutaneous and intravenous administration routes. Determining the substitution dose without appropriate information could prove dangerous for the patient. Benzo Switcher offers you a safer way to do this by using conversion ratios used by your peers and by providing information about the respective bioavailabilities of benzodiazepines. In this way, it partially mitigates the current lack of publications and data on this conversion, which is more common in palliative care.

  • Paid (Orthodose® Pro)
  • New tool
  • One Benzodiazepine is not the same as another
  • Oral and parenteral routes
  • Safer conversion facilitated


For easy conversion of Corticosteroids

Corticodose, the corticosteroid converter included in the Orthodose® app allows you to compare the mineralocorticoid potency of most glucocorticoids used in palliative care, such as for example methylprednisolone and dexamethasone. Corticodose provides you with information on the half-life and mineralocorticoid potency of each corticosteroid. It is available free of charge.

  • Free
  • Half-life
  • Mineralocorticoid potency

Mix & Match

Check, prepare!

Mix&Match lets you check whether or not it is possible to use a particular combination of drugs in the same syringe. It is common practice in palliative care to administer treatment by means of a continuous infusion pump. However, not all drug combinations are authorised. Mix & Match does not contain any information regarding drug interactions, the pharmacokinetics and/or pharmacodynamics of medicines. With Mix&Match you are able to check the compatibility of a drug mix before preparing it.

  • Paid (Orthodose® Pro)
  • New tool
  • Compatibility of drug combinations
  • Updated
  • Subcutaneous and intravenous

Opioid Switcher

Evidence-Based Medicine (EBM) conversion

Opioid Switcher is used to calculate equianalgesic doses for the different opioids used in palliative care. The oral, subcutaneous, intravenous, and transdermal administration routes are all covered. Dose reductions can also be calculated during this conversion operation as recommended in the literature. The list of opioids includes the following drugs: Morphine, Oxycodone, Hydromorphone, Tapentadol, Buprenorphine, Alfentanil, Fentanyl, Sufentanil, Codeine, Tramadol, Dihydrocodeine, Pethidine, Hydrocodone, and Diamorphine. Our equianalgesia tool includes Evidence-Based Medicine (EBM) ratios, making it a unique app for doctors. Methadone was recently included.

  • 2 versions available (free/ paid for full access)
  • Opioid rotation
  • Dose reduction
  • PO, SL, SC, IV, TD
  • Methadone included
  • EBM ratios

Rescue Dose

Rescue dose calculator used in oncology and palliative care

An opioid rescue dose, also called a breakthrough dose, is an additional dose of analgesics administered preferably to patients with cancer in the event of an attack of paroxysmal pain.

It is inseparable from the basic, around-the-clock, treatment with opioids and its integration with this treatment is greatly facilitated by Orthodose®.

Rescue Dose, the only app of its kind, is, however, almost essential for practitioners in the treatment of breakthrough pain with opioids. Used by physicians since 2010.

  • Paid (Orthodose® Pro)
  • Essential in palliative care
  • Management of breakthrough pain
  • The only one of its kind
  • Used for more than 10 years


Checks compatibility for subcutaneous administration

When oral administration is impossible, the subcutaneous route is then often used in palliative care. Sub-Cut offers you a list of compatible medications.

  • Paid (Orthodose® Pro)
  • New tool
  • Limit unnecessary infusions
  • Home care

Opioid intoxication

Treatment of opioid intoxication with severe signs

Poorly prescribed or poorly used opioids may lead to serious and lethal complications. Orthodose® offers rapid access to recommendations for the treatment of severe opioid intoxication. This is, by the way, a recent FDA Drug Safety recommendation (07/23/2020, FDA drug safety).

  • Free
  • Ensures safe drug administration
  • Compliant with FDA recommendations
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